Plasma Therapy

Case by case consent is being given for starting Plasma therapy for patients solemnly affected with Covid-19.  

What is Plasma Therapy? 

Convalescent Plasma therapy involves the utilization of Plasma from a recovered patient of Covid-19. It is surmised that the patient who has recently recuperated from the disease will carry the Antibodies to fight the disease. This Antibody opulent plasma is then given to a patient suffering from an earnest infection, who is probably in the ICU and maybe on the ventilator. Plasma is a component of the whole blood without the cells. It is different from Serum. 

Who is a Recipient? 

An earnestly ill patient suffering from Covid-19 is the recipient. The Antibody affluent Plasma avails the person to fight the infection more vigorously. 

Who is a Donor? 

A patient who has prosperously beaten the infection and has got better recently is a likely Donor – customarily about four weeks from instauration.  

Are some Tests done to visually perceive who can donate and receive this Plasma? 

Just like Blood donation, it is very paramount to ascertain Compatibility. 

Donor factors-Must be salubrious with good Haemoglobin levels 

Test for HIV, Hepatitis B, and Hepatitis C must be negative 

Blood Group and Rh compatibility must be done in ideal cases 

Ideally, Antibody Titres should be done to judge for the efficacy of the Plasma 

Expound the whole process 

In an ideal situation – a person has caught Covid-19 infection and has since recuperated. He is asked if he would relish to donate his plasma in case it is needed for earnest patients. Once his consent is obtained he is kept on the list of potential donors. 

About 28 days later he is called to donate Plasma – ideally, this should be done by a process called Apheresis where only the Plasma is extracted and the blood cells are returned to the patient. This has two advantages: 

The patient does not feel the impuissance/ fatigue which can sometimes transpire after a whole blood transfusion 

Since only Plasma is abstracted the person is potentially able to donate again in a short span of a fortnight or so. 

This Antibody affluent Convalescent Plasma is then stored at a felicitous temperature – like blood in a blood bank. 

A patient is deteriorating in the ICU. The treating team takes a decision or considers the utilization of Convalescent Plasma as a therapeutic option. 

Sanction is taken from Regime agencies to give the therapy. 

Once sanction is granted, the blood of the patient is matched with the Plasma to check for compatibility. If all is fine, the therapy goes through and about 250 ml of the Plasma is given Intra Venous. 

How prosperous is this Treatment?  

It is too anon to verbally express. Initially sanctioned by the WHO for treatment of the Ebola Virus outbreak, this treatment is a component of therapeutic options for a very solemnly ill patient.  

Are there any side effects?  

Though the jeopardy is low there is always the possibility of some reaction to the Plasma which is being used 

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